Dr. Lowe: I must apologize to you for a problem I have in answering your question forthrightly. The problem is that the FDA severely restricts free speech when it comes to products, such as HSF, classified as “dietary supplements,” although many supplements (to speak obliquely) are powerfully health inducing. FDA restrictions dictate that we not relate a dietary supplement to any disease and that we not compare a supplement to a prescription drug. So much for our nation's founding fathers and their love of the open exchange of potentially-useful information.

However, the open access journal Thyroid Science (www.thyroidscience.com) has published two clinical trials in which I compared HSF to a synthetic T3 product. The T3 product, Cynomel, is a high-quality brand that US citizens can legally purchase from off-shore pharmacies without a prescription. That Cynomel isn’t a prescription drug when purchased from an off-shore pharmacy enabled me (at some risk I suppose) to compare Cynomel to HSF. I'll refer you to those
two studies so that you have access to the actual clinical testing of HSF.

1. Lowe, J.C.: Comparison of Cynomel and Hypo Support Formula: their clinical equivalence and differences in their physiological effects. Thyroid Science, 4(3):CLS1-11, 2009. http://www.thyroidscience.com/studies/lowe.2009/lowe.hsf.3.22.09.htm

2. Lowe, J.C.: Comparative effects of Cynomel and Hypo Support Formula. Thyroid Science, 4(10):CR1-8, 2009. http://www.thyroidscience.com/cases/lowe.10.5.09/lowe.hsf.10.5.09.htm

I am presently working with a laboratory to develop a dietary desiccated thyroid product that will be an improvement over HSF. It should be available in about
six weeks. Unit-for-unit, it will be more health enhancing and less expensive than HSF. When the new product is available, Franconia Ltd, the company that owns www.ThyroidScience.us, will make it available at the website.

Again, I apologize for my FDA-zipped lips and the need to write indirectly about the question you asked. If you would prefer to communicate more directly and openly, I'm available for telephone consultations. Of course, we must charge for that service, which to me is a burden placed on health care consumers by FDA restrictions on free speech. But, alas, this is what the US in many ways has become—far too much like Joseph Stalin’s USSR of the 1940s and 1950s.

All best wishes to your wife and you.